Description
These tracks show constrained regions calculated by the Zoonomia Project
- Ultraconserved elements (zooUCEs):
Ultraconserved elements identified from the 241-mammals genome alignment. All regions >=20bp where
at least 235 species aligned and all aligning species are fixed for the same base at every position. N=4,552; 20-190 bp.
- Runs of contiguous constraint (RoCCs):
All genomic regions where contiguous bases have phyloP score > 2.270 (5% FDR) and are therefore under high
constraint. Regions separated by a single base with phyloP < 2.270 were merged. N = 595,535; 20-1,359 bp.
- Unannotated Intergenic Constrained Regions (UNICORNs):
Non-coding regions of the genome that lack annotation in ENCODE3 but show high evolutionary constraint, suggesting function.
Positions with phyloP > 2.270 (5% FDR) within 5bp of each other are grouped into UNICORNs. N = 424,180; 11 - 1,325 bp.
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